I have a 1976 K5 with a 350 crate motor that I’m considering moving towards fuel injection but not sure where to start or what to look at. Any help or direction would be appreciated.
It really depends on your experience and willingness to learn.
GM TBI-based setups have a proven track record of OEM-level reliability but lack the ability to tune or adjust to changes on the engine. Changes like cam, intake, heads, and upgraded exhaust. Retrofitting an earlier truck would require the TBI tank, fuel lines, and a harness to go with the rest of the TBI engine parts. Many a DIY person did this exact upgrade for years before the whole LS swap the world stuff came along.
The performance aftermarket has come to the game with similar Throttle Body-based injection systems with self-learning/tuning ability. FAST, Holley, and others play in this realm. They have options for a secondary fuel reservoir up front to put a higher pressure pump into so you don't have to change the existing tank, but the smarter option is putting in a factory-style TBI tank and pump of the correct pressure for the system you are using to simplify the installation.
Still, TBI-based systems are limited as it still is not as efficient as a multiport injection system. Edelbrock sells a really nice setup that is also self-learning but also tunable if you wanted to go down that rabbit hole.
Depending on what you want to use will dictate other items for the engine like in the ignition/spark department. A GM-based TBI will require the TBI parts for the distributor, coil, and the rest of the sensors. A more basic aftermarket TBI system may not have the ability for timing control, so a basic non-points style Dizzy with mechanical and vacuum advance will work. The higher-end TBI systems and the Multiport will have timing control and will require a dizzy that a computer can control.
The sky is the limit for sure. But it still really comes down to how deep you want to go into it.