OK, for best economy aim for ~1800 rpm at cruise speed on the highway. Without OD you're never gonna see numbers near that low so just keep it in mind for the future.
My combo was 4.56's, SM465 and 39.5's ... 2550 rpm at 65 mph
4.10's, SM 465 and 36's ... 2484 rpm at 65 mph.
Near enough to the same. As long as it's not a commuter you'll be more than fine with that. I was for many years, including the trip down to Moab and back home to Vancouver BC. That's roughly 2500 miles of straight highway driving.
The 6.2 is governed to a max rpm of 3600 rpm, and being a V-8 it doesn't mind revving. You 'may' have seal issues like I did though if it spins those R's for extended periods of time. I came home to a rear main seal that was in need of replacing after BB '03. It may have gone anyways, but I don't think turning ~2600 rpm for 2500 miles helped any.
A turbo on a 6.2 is fine, Banks has had a kit available since the 6.2 was intro'd...in fact GM used the Banks kit as a dealer option before the 6.5 TD was offered. You can't run crazy boost, because the 6.2 has relatively high 21.X:1 CR. Seems 7-12 psi is about it...but that does a lot to wake these up.
I found as long as they're geared a little agressively they move out decently even without the turbo. However, most stock 6.2 rigs got craptastic gearing too.
Rene