IN short. the answer to you question is YES. I used my existin harness in my 1987 K5 when I installed a 1992 TBI 454. I DID have to modify about 70% of the connectors since the 1991 454 TBI had a lot of differect connectors than my factory 87 350TBI, but all the correct wires were threre...I also had to add a a ground here and there (one for the EVRV vacuum solnoid) and a keyed hot 12v+ (again for the EVRV vacuum solinoid. but uther than that, all the wires that were needed for the 454 were already in use on my 350 TBI harness. Luckliy the 454 had the entire harness with it when I bout it so I just cut off the connectors I needed and added them to my existing harness. I think older 454 TBI units have the same connectors (probably 1987 through 1990 or 1991) If I were you just go to a yard and grab the TBI unit, ECM, TBI intake, and the entire wiring harness. you COULD just cut off the harness at the firewall but I would just take the extra time to get the WHOLE thing...
The interchageability of the sensors will be dependent on the year of 454 FI you get. Like I said, my 1992 TBI had a good mix of parts that were interchangeable between the 350 and 454...but an older 454 unit may be 100% interchangable. On mine, the IAC, TPS, EGR solinoid, and MAP sensor were different between the 2 motors. The CTS, Knock sensor and O2 sensor, and the Dist connectors were all good to go...
You fuel pump WILL work as long as it is up to snuff...My truck had a dying fuel pump but it was still doing well enough to feed the 350. As soon as I bolted the 454 in, all my old tired FP could do was allow the 454 to idle.. The AC Delco replacement pumps are the same for both 350 and 454 applications (part # EP386)
Fuel lines were a direct bolt up, as was the starter.
Good luck and drop me a line with any more questions...I deff. learned a lot during my 454 TBI swap and would be MORE than happy to share what I learned...
Chris /forums/images/graemlins/peace.gif