Absolutely!
Your travel speed across the ground will be different at 100:1 with a 35" tire (slower) than with a 44" tire (faster).
The thinking man (which we know you are) will consider both the crawl ratio
and the tire circumference as determining factors for how the truck will perform offroad.
I've got some calcs somewhere that show the feet/minute that various setups would travel at 650RPM (idle basically). Consider that 1MPH is equal to about 88 feet/minute of travel speed, and these types of crawl ratios put the truck down at around 60 feet/minute.