Any square body K20will be mostly a direct swap. Things like the rear u-bolts and plates, u-joint at the rear axle, rear driveshaft length and front brake caliper hoses & hardware (depending on the donor year) are the only hurdles I can think of.
You'll likely get better gears with the K20 axles so no real down side. Beware that in the 80's there were light and heavy duty K20's which dictated different rear axles (semi floater vs full floater 14 bolts), the semi floater is still a good axle but it's not comparable to the full floater that most people use.