as others mentioned the fiberglass reinforced filler is good stuff for "thicker" applications. always best to skimcoat over that with regular mud, little more primer friendly. also the glass reinforced stuff should always be used over patch panel seams. that is an area prone to cracking.
also keep in mind that fillers have come a long way these days and a quality filler is likely not to crack even when relatively thick. but yes, metalwork when possible...