Cam choice
With the Vortec heads you are limited to about 0.450" of lift, unless you have the spring seats machined. Assuming the engine is a roller cam, I would look into a cam that gives you the most lift you can get, without going over about 215 degrees of duration at 0.050. Any higher than that and your getting into a "Midrange" cam that you really don't need with an overdrive tranny. You want alot of bottom end torque to get you going quickly off the line with those big tires, and towing your boat. With an overdrive tranny the engine is rarely going to to see the high side of 3500 rpm's, and cruise at around 2 grand. I don't know what the emissions laws are where you live, but you want headers and a free flowing exhaust. Dual setups work well on these trucks with a 2 1/2 in pipe. The compression ratio in that motor is about 9.1/1 stock. That's plenty for a low duration cam to still run on pump gas. The GM intakes are pretty good, and there's really no need to change it. Th GM Vortec intake manifold gaskets are pretty flimsy, and fail pretty quickly. Use a good aftermarket brand like Fel-Pro or Rol. If you like, E-mail me through this site, and I can send you some Dyno-sim charts with a few recommended cams in them, and you can see where the power will be. Or you can call the helpline of the cam manufacturer you want to deal with, and have them recommend something. I'm partial to Comp Cams myself, but I've gotten good results with other manufacturers depending on the application.