I've had both an '82 Blazer and an '84 K20. I built the blazer and ran it hard on the Arizona rocks..... If I had to do it again I would use the K20. It is noticeably thicker than the blazer frame.
After 2 years of hard wheeling the blazer frame had:
cracked at the the steering box
cracked at the passenger upper rear shock mount
bent on the top side of both frame rails about in the middle of the truck
a big hump in the top of the driver side frame rail at about the firewall
The front frame rails were laid over a couple degrees
The frame was so bent I couldn't load it on the trailer straight and it tracked about 6 inches off like those busted rebuilds you see driving sideways down the highway
Most of that could have been avoided had I built a good cage that helped support the frame, made custom mounts for the rear shocks, and used the ORD steering box repair and brace.
I still prefer to start with a stronger base.... But that's my opinion