To be honest, unless you are running a huge motor, I don't think you can lose either way. (MPFI seems to be a bit easier, if costlier, getting to work on larger, high RPM motors)
The advantage you'll see from EFI in one of these trucks is more about overall driveability and running at angles than it is anything else.
Some great features if you like to tinker (like programming your own PROM's) but other than that, it's simply things like not having to deal with a picky choke, "losing" tune, cold starts, hot starts, etc.
As common and fairly cheap as the TBI trucks are, I don't think it's a wild stretch to say that installing a TBI system and seeing what you think before making the jump to MPFI is unrealistic. Neither system is more complex than the other (much, lol) so if you install TBI and like it, stay with it. Cheap, and it does what you ask. If you need more after that, consider selling it off to partially finance MPFI. If you do it right, you'll already have all the fuel and power issues figured out from TBI, so it would be pretty simple after you understand TBI.
I run TPI because I got it fairly cheap, and I knew the people I was getting it from. Aftermarket MPFI (to me) is crazy expensive, but I understand that is because the components are expensive, and the volume of sales isn't there to bring the cost way down.
What are your current beefs with a carb? If you want to go injection because it's "cool" (no arguments there

) then I'd say just go TBI. If you NEED MPFI for whatever your driving demands are, then go that way. If you are unsure if you need MPFI, start with TBI, see if it works for you.
Either way it's not a 4 hour project for someone that has never done it before (even if you've done it 10 times it's not a 4 hour project) but it's doable as long as you are willing to spend the time to do it right, so it's reliable in the long run, especially as a DD. Are you able to put it up for a week or two while doing an install and working out any bugs?
My opinions anyway.