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Side Window change 101
The seals are two part the rubber and a rubber insert locking rubber. I believe the main seal is like $99.00
Here is how I did my window change it was easy to do. You will need two flat head screw drivers and spray bottle of soapy water. A very small flat head to reinstall lock rubber. *if you have a window install tool works best about $5.00 for it. Looks like a pick with a pigs tail end.
1.) looking at window from outside you will see a little metal clip in the middle of rubber at the bottom. Take a small screw driver and pop that out.
2.) You will now see a small gap between the inner rubber strip. Take one end of it and pull it out in a lifting manor (away from truck).
3.) Now you will need two flat head screw drivers. Start a few inches from the lower rear corner and insert one screw driver in under the lip of the metal frame. Next spray some soapy liquid on rubber and insert other screw driver and work it around to lift the frame/glass out of rubber. *works best going to top.
4.) Once you get the rear upper corner out it is a breeze. Keep going till you have most of the top out of rubber. At this point you can pull the frame/glass out.
5.) I took the seals out and cleaned them in warm water to get crude and old black goop off. I used a butter knife to get it clean (
DO NOT LET YOUR WIFE SEE YOU DO THIS).
6.) After they were dry I put a thin bead of black RTV on the fiberglass lip and placed rubber onto it.
7.) I then placed the lip of the frame/glass in to the front corner of rubber and started to wards the rear. Using the screw driver to pop the outer lip out at the rear and worked on up and over to toward the front. *you will need the soapy liquid from time to time.
8.) Once you have it in you will take the thin rubber piece that you pulled in step 2. Start in the middle bottom and insert it into the gap in the rubber *I used a small flat head to push the upper edge down into channel. The best way to describe this motion is kind of like a wrist flick or reverse knock.
9.) Now if you did every thing right you should have a little extra locking rubber when you get to bottom *(stretches when you pull it). Cut this as close to the other end as you can (about 1/4 inch).
10.) Now you will replace the metal clip pull both ends out just so you can slide them into the clip. Now press it into the grove.
http://coloradok5.com/forums/showthread.php?t=195272&highlight=butter+knife
To replace glass in the window your on your own. I would think a glass company....
I know to get the vent window off you need to pull the screws out, but the screws are steel, the frame is aluminum, with the resultant corrosion, the screws normally can't be removed. One reason I tossed the sliders and went with solids. 
