PAO group IV base stocks are made entirely in a lab. and they are better oils.
PAO's are still a petroleum hydrocarbon, they are just different petroleum hydrocarbons than what conventional oil is made from.
Synthetic means "synthesized", not "made from something other than what comes out of the ground"..in this case, the molecules are refined and re - refined ( synthesized) until they are all uniform size.. that's where synthetics are good - the uniform size enables the oils to pump faster and flow easier in extreme conditions...nowadays though, group II and three oils can have the same level of refinement, and not be PAO based.
problem with the PAO base is that it does attack seals over time, causing leaks, and the additives don't mix well with them..they drop out of suspension due to thermal breakdown...so the oil companies went to a PAO / ester blend ( think RP's "synerlec" technology) so the seal degradation problem isn't so prevalent..esters are nice to seals, but like moisture.
the other thing is that PAO is an expensive basestock, so in a "true PAO oil" nowadays, you tend to see a little PAO, a lot of ester, and a lot of solvents and filler..filler being the liquidized plastic used to enable the oil's viscosity to swing from a 5W to a 30W.
TIP: The closer together the numbers are ( 10w30 compared to 5w40 ) the less plastics are in the oil..the viscosity doesn't need to move that much.
bottom line oil companies started selling group II & III oils for a reason, and that was to control costs while delivering a useful product...the EPA tells the oil companies how to make their oil, then it's up to the marketing departments to put a happy face on it and create buzzwords so we buy it..
all of the antiwear additives have been reduced anyway, so if you are going to do extended drain intervals, have the oil analyzed, and if you are into it, study the tech sheets and MSDS sheets that are available from the company..very enlightening.
I stand by my statement..buy what your budget allows, and dump it at the drain interval, and if are gonna go further than that, have it analyzed. don't trust the label on the bottle.