450 is definitely the max without some machine work on the heads, or the bottom of the spring retainers for a little more clearance.
I had a 440 lift cam in my '89 Blazer /forums/images/graemlins/k5.gif for a while. It ran fine, but it was close enough to trash the slip-over valve seals on all of the intake valves after about 2,000 miles. I have since rebuilt the engine to a 383 and remedied that problem.
I would also suggest getting a cam recommendation from the cam company of your choice.