Has the truck been driven much before you took this "long" trip?....reason I ask,is you say it started after a drive in rainy weather---if the fuel filler pipe going to the tank has rusted thru,as they often do,water spraying off the tires will find its way into the gas tank---I took a truck in to do an electric fuel pump replacement one day,and the tank was 3/4 full--only trouble was the owner said he had driven it a lot farther than he usually could on a full tank,before it started dying out and running very sluggishly...when I pulled the tank out and removed the fuel pump,it had a good 5 gallons of water in the gas!--plus a lot of dead leaves,sand,and other crud that got tossed into the hole in the filler pipe that had flaked off of it!...
After I replaced the fuel pump & dumped the crappy gas/water & crud mix out of the tank,the truck ran so much better,the guy actually squealed the tires as he pulled away from my driveway--said it had never had that much power since he owned it!...I found a recently replaced fuel filler neck pipe at a junkyard on a similar truck,that was good luck,because new ones are over 100 bucks..I paid 20 for it,still had a GM part sticker on it,looked brand new!...