I run a 2006 NV4500/205 in my ’78 K10 behind an 8.1L and last winter also swapped a 1998 NV4500 into my ’89 Suburban behind a TBI 5.7L with a NP241 tcase. Both rigs have the later transmissions with the 5.61 granny gear instead of the early ones with the nice 6.34 granny gear. On the other hand, the later ones also shift much nicer. Then I have a somewhat rare 2001 Silverado 2500HD that I bought new 13 years ago with an 8.1L and ZF S6-650 6 speed manual. Over the years I’ve had several SM465 and SM420’s in various GM trucks.
Anyway, out of all the GM manuals, the NV4500 is my absolute favorite of all of them hands down. It is no sportscar transmission but it is about as close to one as you can get in a fullsize truck. It may not be as strong as a 465 but it is not a dump truck archaic shifting thing either. After being used to driving the NV4500 in my K10, I couldn’t stand to drive the SM465 in the Suburban anymore so that 465 in the Burb had to go. The lack of overdrive helped make it an easy decision. Now, the ZF 6 speed in my Silverado is a disaster. It has the most ridiculous shift pattern and clumsy gates of any manual transmission I’ve ever driven but I doubt that trans will ever break. The ZF’s are anvil strong!
So that is the good stuff going for the NV4500….the bad side of the NV4500 is the later version (1995-2006) has a horrible first gear. I badly miss the 6.34 granny gear of the SM465’s before them. The deep granny gear was so nice when descending a vertical grade. Then there is all of the 5th gear war stories. The NV4500 in my K10 was swapped in 3 years ago and 14,000 miles later 5th gear started screaming on my way home from Death Valley last spring. I can’t even blame the 5th gear nut as the culprit because I was using an Advance Adapters kit where the mainshaft is cut off and the 5th gear nut isn’t even used. It uses a collar to hold 5th gear and the sleeve between the transfercase and transmainshaft help hold 5th gear in place. Once it was apart we found what we suspected…the 5th gear cog was rocking on the mainshaft like the typical loose nut issue but yet there is no nut to back off and everything holding 5th gear in place seemed to be solid with zero end play.
While it was apart getting a fresh mainshaft and 5th gear cog I went with a round pattern 205 this time with no adapters between the trans and tcase as well as added two big ass coolers to the PTO plate covers for added fluid capacity. We’ll see how well it lasts this time and “if” the 5th gear nut backing off stories come true. If it

s on me again it is getting replaced with an Allison!
One theory with my low mileage NV4500 5th gear issue is the fact I constantly lug the truck. By lugging it, I mean that I shift it at very low RPM’s. It is not uncommon for me to be in 5th gear before 40 MPH. The 8.1L is like a diesel where it has the torque to lug itself around at low RPM’s but in high gears. There is a popular opinion lugging them is just as bad on them as the diesels vibrating the mainshaft nut loose. The fact the truck weighs 8,000 lbs. probably doesn't help the 5th gear much when I lug it either. In hindsight I really wish I would have installed the mainshaft damper while I had it apart a few weeks ago to help reduce those harmonics if there is any truth in the lugging theory. I guess time will tell! Meanwhile I am keeping my eyes open for an Allison 2200.
At least the NV4500's are an easy swap and look sexy underneath tho!
'78 K10
'89 Suburban