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I do it. Really the issue is what you will use for a bead lock. The radials tend to be thinner at the bead, so you use a little wider insert than the bias plys use. TrailWorthy sells the same PVC inserts for all tires and says that for the most part you just hammer the nuts with an impact. For certain tires you have to trim the insert thinner.
PVCs are custom cut to length but work with many different tires. Larger tires may require a custom width to work properly since the bead thickness on the tires is greater. If you plan to run 40s and larger please contact us to get your PVCs trimmed down.