same as any other engine
crank a can of compression into it
get the best heads you can find to feed it
free flowing exhaust with as little back pressure as possible (this means no Flowmasters)
at least 10:1 compression, I would go higher
overkill the cylinder heads with a race oriented selection
look at what worked in PHR Enginemaster Challenge
over 12.5:1 on 92 octane pump gas
I was following the Ford 351C camps, Kaase won with a 410" 351C at about 699hp at a streetable rpm
another one, Dave MacLain team 335, that put down over 650hp was at 12.3:1 and never had a hint of detonation
the rules were twisted to keep the 351C out of the game but even with the vintage stock factory block it came out on top
I think 6 of the top 10 were Fords
compression makes power, heads make power, intake manifolding makes power