1st: damn that truck is sexy!
2nd: I'm not sure I caught where you live? If it's primarily flat, you'll be fine with the gearing. Keeping in mind that granny low is 6.55, so no problem getting off the light. Just an issue if climbing a hill like everyone else has said.
I have the sm465 and 33's and have gone from 3.73 to 4.11 and, with either gearing, have not once had to downshift on the highway (even up a 7% grade). I assume you'd be doing some shifting, though. Also, I don't have a lift and roll 33's; just takes a quick snip of the inside front portion of the lower fender.
Finally, not sure the height of your garage door, but I measured my "factory" house to fit my K5 with 4" lift and 35's. Still have yet to do the work. Also remember that every inch of tire only lifts the truck 1/2 of that.