GM did change the fill neck diameter at some point. AFAIK however that was done once they went to the hidden fuel cap, so I don't think it will be something you can just swap out like you can with the hidden cap setups, since the metal fill portion is interchangeable.
GM did not send these things out vapor locking, running fuel lines outside the frame is at best a bad idea IMO. I have ripped wiring off that was run outside the frame rail, and that's not four wheeling, there is no way I'd run fuel that way. If your EFI uses a return line, that can HELP with a vapor lock issue (as well as the pressure), but it uses the tank and lines as cooling, so any heat dumped into the fuel along the way will heat the tank and raise the fuel temp.
Run a tank breather. The best method is through a vapor canister (EVAP) and back into the throttle body, but theoretically it can be vented anywhere. My experience with this is that if you just vent it, you will smell fuel often. My experience with a vented gas cap on the K5 is that when the tank is full, fuel can/will leak out when it sloshes, or if climbing a relatively steep hill.
FWIW the spring in the lower radiator hose is a factory deal, because they used to fill them with a vacuum system, and the hose would collapse. It is not needed in a pressurized cooling system, factory configuration, working properly.