I'm thinking a programmable ignition curve would be nice(although it must be very simple for me to do) along with EFI...might as well wire and tune them both in at the same time?
Zim, you have several options to do that.
If you want to stick with simple self tuning systems I would suggest EZ-EFI along with an MSD Digital Programmable 6AL-2. The EZ-EFI doesn't require a different intake (although if you have a standard performer you should get a different one anyway!). The EZ-EFI is self tuning and you can fully program your ignition timing with that MSD ignition box. The pogrammable MSD box is about $360, and the EZ-EFI is about $2k.
The next step up would be the EZ-EFI multi port kits. They use the simple self tuning EFI brain but use a multi port 8 injector intake. Those probably run about $3k, and you would need the MSD box to control timing.
Then there is fully programmable EFI with timing and everything. FAST XFI does have the self learning feature of the EZ-EI built in now. And controls timing and everything, and can be used with boost, nitrous, etc. The FAST box will not control a trans, but that doens't matter to you. The ful out FAST system is probabyl around $4k, I would just use a standard 6A ignitino box with that system, because the system will control the spark just like the programmable MSD box would, but it's all built in.
Now if you want the ultimate in control and technology, then look at Big Stuff 3. Meaney is the founder of digital fuel injection (he is the one that developed the base systems for Accel, FAST, Holley, etc) and currently has the most capable controller on the planet. It can control multiple injectors, (up to 24), transmission, 2 fuel pumps, 2 fan stages, nitrous stages, as well as built in coil pack drivers for newer LS style and other multiple coil systems and other stuff I'm not mentioning for boost, etc. Did you know they are actually misfiring the engines on purpose at the tree so the combustion is late in the exhaust cycle and helps spool up the turbo very rapidly? Sounds horrible but the turbo spools up very quickly and then they shut it off as soon as the trans brake is released and immediately return to a properly timed engine. No other single controller box can controll all of that at once, including injectors, timing, coil packs, and transmissions. Meaney lives in MI about 20 minutes from my previous house up there.
http://bigstuff3.com/
So you need to decide, do you want simple EZ-EFI or fully programmable or somewhere in between. All of these setups will require you lockout the distributor. Nothing wrong with a standard HEI coil unless you start getting up to 135 mJ and 530V at the primary coil or so. Once you get there you start burning up the internal HEI coils and an external coil is more relaible.
Now, yes, the atomic EFI from MSD will control the timing, but I would rather have the EZ-EFIs high pressure return style fuel system with the injectors under the throttle blades and a seperate programmable ignition box for the timing than the atomic EFI with the injectors above the throttle plates like old fashioned GM TBI.
On my truck I don't even have programmable ignition. It works perfectly. The most gain is from the closed loop fuel control of the EFI. Once the timing is set it never changes anyway, it's not like the closed loop where if the fuel is off because of altitude or temperature that it self corrects. When the timing curve is set, it stays that way, even with EFI. Unless you implement a knock sensor, which most aftermarket EFIs don't use, but they are optional. My ignition is an old MSD 6A with a stock HEI coil. I did upgrade the little bushing above the rotor and the plug wires to MSD superconductors though. That makes darn sure all the energy is getting to the plug. The stock bushing has about 10,000 ohms, and the MSD bushing is approaching zero ohms. Also, the superconductor wires have less than 50 ohms/ft of resistance while still being EMI suppressive wires. standard wires are usually 700 - 900 ohms/ft. That means most super conductor wires are 100 - 200 ohms, where most other wires are over 2000 ohms each. I really like MSD ignition products.
All the programmable ignitions, whether it be MSD box or EFI, will require you to lockout the dizzy and phase it so it is in sync with the computer. Simple to do, I can tell you how over the phone if you need.
EDIT: It looks like Holley caught up in the coil driver department and can now control the coil packs, injectors, and tranny as well in their dominator ECU. Haven't read there user manual to see the tranny controller interface though and how they interact with everything else such as nitrous, boost, misfires, trans brakes, etc. Although none of that matters for you, including the coil packs or tranny.