Ahh rust repair 
I'd get your truck prepped and make your initial cuts on it first. Leave your patch as big as possible until you know how much of it you need. Unfortunately, when there's a hole already you're bound to find more around it that won't be salvageable. I'm guessing you'll need to cut out at least 4-5" past the hole to find metal that is thick enough to weld.
I'd buy a spot weld cutter too. They're cheap and won't heat up/warp the sheet metal like the grinder will when removing the spot welds.
Take lots of pics and ask as many questions as you need to
You got this 

I'd get your truck prepped and make your initial cuts on it first. Leave your patch as big as possible until you know how much of it you need. Unfortunately, when there's a hole already you're bound to find more around it that won't be salvageable. I'm guessing you'll need to cut out at least 4-5" past the hole to find metal that is thick enough to weld.
I'd buy a spot weld cutter too. They're cheap and won't heat up/warp the sheet metal like the grinder will when removing the spot welds.
Take lots of pics and ask as many questions as you need to







